ODCs

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4 OMIM references -
4 associated genes
19 signs/symptoms

COMMON GENES: 2
PROTEIN INTERACTIONS: 1
COMMON SIGNS: 3

4 OMIM references -
2 associated genes
5 signs/symptoms

Benign familial infantile seizures

Benign familial neonatal seizures


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KCNQ2	(0.83)	KCNQ3

Citations in the biomedical literature:

Benign familial infantile seizures		Benign familial neonatal seizures
	Synonym(s): - BFIE - BFIS - Benign familial infantile convulsions - Benign familial infantile epilepsy		Synonym(s): - Benign familial neonatal convulsions - Benign familial neonatal epilepsy

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Diseases of the nervous system -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant

	External references: 4 OMIM references - No MeSH references		External references: 4 OMIM references - 2 MeSH references: C535466 / D020936


COMMON SIGNS	- Autosomal dominant inheritance - Hypertonia / spasticity / rigidity / stiffness - Seizures / epilepsy / absences / spasms / status epilepticus

Benign familial infantile seizures		Benign familial neonatal seizures
	Very frequent - Anomalies of eyelids, eyelashes and lacrimal system - Anomalies of eyes and vision - Motor deficit / trouble - Movement disorder - Myoclonus / fasciculations - Obnubilation / coma / lethargia / desorientation Frequent - Chorea / athetosis / choreoathetosis / choreic syndrome - Hyperkinesia / dyskinesia - Hypotonia - Paresthesia / dysesthesia / hypoesthesia / anesthesia / numbness Occasional - Asthenia / fatigue / weakness - Delirium / hallucination - Facial pain / cephalalgia / migraine - Nausea / vomiting / regurgitation / merycism / hyperemesis - Speech troubles / aphasia / dysphasia / echolalia / mutism / logorrhea / dysprosodia - Troubles of memory / amnesia / hypermnesia		Very frequent - Autosomal recessive inheritance Occasional - Intellectual deficit / mental / psychomotor retardation / learning disability